Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

Nature | August 2016| Summary Mice deficient in the DNA excision-repair gene Ercc1 (Ercc1∆/−) show numerous accelerated ageing features that limit their lifespan to 4-6 months1, 2, 3, 4. They also exhibit a ‘survival response’, which suppresses growth and enhances cellular maintenance. Such a response resembles the anti-ageing response induced by dietary restriction [...]

By |2017-06-20T10:08:02+01:00August 25th, 2016|Papers|Comments Off on Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

Future of Aging

September 23-24 - 2016 | Warsaw, Poland | We cordially invite you to share and discuss your views on one of the most important and urgent issues – THE FUTURE OF AGEING. Most of us now expect to live a long life and will experience ageing and old age. Understanding the biological, biomedical, demographic and psycho-social aspects of ageing is [...]

By |2017-01-12T16:03:04+01:00August 16th, 2016|Meetings|Comments Off on Future of Aging

Healthy Ageing Seminar

Augustus 30-31 - 2016 | Gothenburg, Sweden | Our life expectancy is increasing. But we don’t just want to live long – we also want to maintain our health. As the ageing population rapidly becomes one of our biggest challenges, research on ageing grows into a hot and important field. We would therefore like to welcome [...]

By |2017-01-12T16:04:53+01:00August 16th, 2016|Meetings|Comments Off on Healthy Ageing Seminar

Newsletter 1 – July 2016

Following the inspirational kick- off meeting we bring out the first newsletter of the association. In the newsletter you will find interesting information about the Kick- off meeting. You will also find a brief summary of a Lorentz meeting on Ageing Research which took place in January of this year. Click here  to open the newsletter. Would you like [...]

By |2017-01-12T16:21:16+01:00August 8th, 2016|Newsletters|Comments Off on Newsletter 1 – July 2016

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors

Edyta E. Wojtowicz9, Eric R. Lechman9, Karin G. Hermans9, Erwin M. Schoof, Erno Wienholds, Ruth Isserlin, Peter A. van Veelen, Mathilde J.C. Broekhuis,George M.C. Janssen, Aaron Trotman-Grant, Stephanie M. Dobson, Gabriela Krivdova, Jantje Elzinga, James Kennedy, Olga I. Gan, Ankit Sinha, Vladimir Ignatchenko, Thomas Kislinger, Bertien Dethmers-Ausema, Ellen Weersing, Mir Farshid Alemdehy, Hans W.J. de Looper, Gary D. Bader, Martha Ritsema, Stefan J. Erkeland, Leonid V. Bystrykh10, John E. Dick10, Gerald de Haan10  9Co-first author, 10Co-senior author Umbilical cord blood (CB) is a convenient and broadly used source of hematopoietic stem cells (HSCs) for allogeneic stem cell transplantation. However, [...]

By |2017-03-06T10:59:09+01:00August 8th, 2016|Papers|Comments Off on Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors

Lorentz-Meeting 6-8th of January 2016

Translational Aging Research: Challenges and Opportunities The aim of the workshop is to generate a roadmap of translational research on ageing by discussing compelling results obtained in animal models and human studies. The translational roadmap will be based on observations in cohort and clinical studies, amenable mechanisms investigated in humans and animal models, experimental designs [...]

By |2017-01-12T16:16:47+01:00August 8th, 2016|News|Comments Off on Lorentz-Meeting 6-8th of January 2016

Biology of Aging: Paving the way for Healthy Aging

October 19-20 - 2016 | Montreal, Canada | The Sherbrooke Research Center on Aging is organizing its second international Symposium on the Biology of Aging. After the success of its first theme “from Cells to Clinics” this Symposium aims at exchanging on the topic of healthy aging and associated pathways. Leading experts will present their newest [...]

By |2017-01-12T16:07:13+01:00August 8th, 2016|Meetings|Comments Off on Biology of Aging: Paving the way for Healthy Aging