Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms 

Genome Biology | September 2016 | Background Epigenetic change is a hallmark of ageing but its link to ageing mechanisms in humans remains poorly understood. While DNA methylation at many CpG sites closely tracks chronological age, DNA methylation changes relevant to biological age are expected to gradually dissociate from chronological age, mirroring the increased heterogeneity [...]

By |2016-12-20T09:17:27+01:00December 20th, 2016|Papers|Comments Off on Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms 

Newsletter 2

The DuSRA would like to give young researchers, engaged in ageing research, the opportunity to present themselves by writing an article about their scientific research. The articles will be posted on our website so all members can get to know these researchers. Would you like to read the whole newsletter? Click here!

By |2017-01-12T16:16:03+01:00December 19th, 2016|News, Newsletters|Comments Off on Newsletter 2

Lipid Mediators in Ageing and Disease

January 5-6 - 2017 Aston University, UK A Biochemical Society Focused Meeting Enzymatic and non-enzymatic oxidation of polyunsaturated fatty acids leads to the formation of biologically active metabolites, known as lipid mediators. These can be exported extracellularly, and then sequestrated rapidly to stimulate cellular autocrine or paracrine [...]

By |2017-01-12T16:19:10+01:00November 22nd, 2016|Meetings|Comments Off on Lipid Mediators in Ageing and Disease

2016 Eurosymposium on Healthy Ageing

September 29 - October 1 - 2016 | Brussels, Belgium | The Eurosymposium on Healthy Ageing (EHA) is a biannual conference organized for the first time in 2012. This meeting will highlight the cutting-edge of knowledge in the field of biogerontology and provide a unique opportunity for researchers, government officials, biotech executives, and advocates from [...]

By |2017-01-12T16:19:57+01:00September 5th, 2016|Meetings|Comments Off on 2016 Eurosymposium on Healthy Ageing

Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

Nature | August 2016| Summary Mice deficient in the DNA excision-repair gene Ercc1 (Ercc1∆/−) show numerous accelerated ageing features that limit their lifespan to 4-6 months1, 2, 3, 4. They also exhibit a ‘survival response’, which suppresses growth and enhances cellular maintenance. Such a response resembles the anti-ageing response induced by dietary restriction [...]

By |2017-06-20T10:08:02+01:00August 25th, 2016|Papers|Comments Off on Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

Future of Aging

September 23-24 - 2016 | Warsaw, Poland | We cordially invite you to share and discuss your views on one of the most important and urgent issues – THE FUTURE OF AGEING. Most of us now expect to live a long life and will experience ageing and old age. Understanding the biological, biomedical, demographic and psycho-social aspects of ageing is [...]

By |2017-01-12T16:03:04+01:00August 16th, 2016|Meetings|Comments Off on Future of Aging

Healthy Ageing Seminar

Augustus 30-31 - 2016 | Gothenburg, Sweden | Our life expectancy is increasing. But we don’t just want to live long – we also want to maintain our health. As the ageing population rapidly becomes one of our biggest challenges, research on ageing grows into a hot and important field. We would therefore like to welcome [...]

By |2017-01-12T16:04:53+01:00August 16th, 2016|Meetings|Comments Off on Healthy Ageing Seminar

Newsletter 1 – July 2016

Following the inspirational kick- off meeting we bring out the first newsletter of the association. In the newsletter you will find interesting information about the Kick- off meeting. You will also find a brief summary of a Lorentz meeting on Ageing Research which took place in January of this year. Click here  to open the newsletter. Would you like [...]

By |2017-01-12T16:21:16+01:00August 8th, 2016|Newsletters|Comments Off on Newsletter 1 – July 2016

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors

Edyta E. Wojtowicz9, Eric R. Lechman9, Karin G. Hermans9, Erwin M. Schoof, Erno Wienholds, Ruth Isserlin, Peter A. van Veelen, Mathilde J.C. Broekhuis,George M.C. Janssen, Aaron Trotman-Grant, Stephanie M. Dobson, Gabriela Krivdova, Jantje Elzinga, James Kennedy, Olga I. Gan, Ankit Sinha, Vladimir Ignatchenko, Thomas Kislinger, Bertien Dethmers-Ausema, Ellen Weersing, Mir Farshid Alemdehy, Hans W.J. de Looper, Gary D. Bader, Martha Ritsema, Stefan J. Erkeland, Leonid V. Bystrykh10, John E. Dick10, Gerald de Haan10  9Co-first author, 10Co-senior author Umbilical cord blood (CB) is a convenient and broadly used source of hematopoietic stem cells (HSCs) for allogeneic stem cell transplantation. However, [...]

By |2017-03-06T10:59:09+01:00August 8th, 2016|Papers|Comments Off on Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors
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