Yara van Holstein published a paper “The performance of metabolomics-based prediction scores for mortality in older patients with solid tumors” in GeroScience in July 2024 Prognostic information is needed to balance benefits and risks of cancer treatment in older patients. Metabolomics-based scores were previously developed to predict 5- and 10-year mortality (MetaboHealth) and biological [...]

Kerstin Schorr published a narrative review "A plant-based diet index to study the relation between diet and disease risk among adults: a narrative review" in the Journal of Nutrition, Health and Aging in June 2024 Plant-based diets (PBD) may offer various health benefits and contribute to a sustainable way of life, but, if not [...]

Ynte Biemans published a paper "Identifying the relation between food groups and biological ageing: a data-driven approach" in Age and Ageing in May 2024 Heterogeneity in ageing rates highlights the need for research into lifestyle factors that contribute to successful ageing. Biological age, estimated by epigenetic clocks, is a more accurate measure of ageing [...]

Marije Sluiskes et al. published a paper "The AccelerAge framework: A new statistical approach to predict biological age based on time-to-event data" in European Journal of Epidemiology in April 2024 They compare predictors based on the AccelerAge framework to a predictor based on the GrimAge predictor, which is considered one of the best-performing biological [...]

Annelien de Kat et al. published a paper “Late reproduction is associated with extended female survival but not with familial longevity” in Reproductive BioMedicine Online in April 2024! “They concluded that female reproductive health associates with a longer lifespan, though women from long-lived families do not show extended reproductive health. Other factors in somatic [...]

Marije Sluiskes et al. published a paper "Clarifying the biological and statistical assumptions of cross-sectional biological age predictors: an elaborate illustration using synthetic and real data" in BMC Medical Research Methodology in March 2024 Their main conclusion was that cross-sectional methods for predicting biological age commonly use the untestable identical-association assumption, which previous literature [...]

Sergio Andreu-Sánchez et al. published a paper "Unraveling interindividual variation of trimethylamine N‐oxide and its precursors at the population level" in iMeta in March 2024 Trimethylamine N-oxide (TMAO) is a circulating microbiome-derived metabolite implicated in the development of atherosclerosis and cardiovascular disease (CVD). They investigated whether plasma levels of TMAO, its precursors (betaine, carnitine, [...]