J Gerontol A Biol Sci Med Science | November 2016 | Abstract: Background: Sarcopenia, or the loss of muscle mass and strength, is known to increase the risk for falls and (hip) fractures in older people. The objective of this study was to assess the skeletal muscle fiber characteristics in elderly female hip [...]
European Historical Population Samples Network | 31-01-2017 | Abstract The limits to human lifespan are a widely discussed topic. Yet, later-life mortality and longevity are generally studied from a genetic perspective, while the social dimension has received less attention. This paper gives a systematic overview of trends in later-life mortality and longevity for [...]
Aging Cell | 23-09-2017| Summary Calorie restriction (CR) is a dietary regimen that supports healthy aging. In this study, we investigated the systemic and liver-specific responses caused by a diet switch to a medium-fat (MF) diet in 24-month-old lifelong, CR-exposed mice. This study aimed to increase the knowledge base on dietary alterations of [...]
E life Sciences| 30 april 2018 Abstract Ageing is associated with physical decline and the development of age-related diseases such as metabolic disorders and cancer. Few conditions are known that attenuate the adverse effects of ageing, including calorie restriction (CR) and reduced signalling through the mechanistic target of rapamycin complex 1 (mTORC1) pathway. Synthesis [...]
Horizon - The EU Research & Innovation Magazine 5 juli 2018 The regenerative abilities of the flatworm Macrostomum lignano serve as a model for how humans might regenerate tissues. Image credit - Flickr/ Lukas Schärer, licensed under CC BY-SA 2.0 Research into the remarkable regenerative powers of worms and the insights they can give [...]
Persbericht LUMC - 7 januari 2019 Een lang leven is erfelijk, maar dat geldt primair voor personen uit families waarvan meerdere leden behoren tot de top tien procent overlevers van hun generatie. In de genen van deze families ligt waarschijnlijk de sleutel tot een lang leven. Dat schrijven onderzoekers van het Leids Universitair Medisch [...]
Dear VOILA-partner, we are happy to publish our second VOILA-newsletter. You can read about updates from other RL's. We wish you all a nice summer holiday and we hope to see you all soon. Best wishes, Eline, Marian, Frans and Joyce Open newsletter
Prestigious ZonMw Open Competition grant awarded to LUMC, VU and RIVM Prestigious ZonMw Open Competition grant awarded to LUMC, VU and RIVM Our life expectancy keeps increasing on a global scale. The increase in healthy lifespan, however, is lagging behind. Members of long-lived families often remain disease-free into exceptionally old ages. How is [...]
The goal of RISE-WELL is to improve SWB and QOL of elderly European citizens to obtain positive individual health outcomes and to promote future translational research. The approach of the consortium has been to design cutting-edge WPs and ESR projects. Scientific need: Mental health and emotional well-being during old age (60+) should be regarded as [...]
This online summer course will stimulate international collaborations between students from Brazil and Leiden. The course will provide an introduction to the use of big data analysis in health and disease. The programme, including theory and practical modules, will focus on diverse hospital data, “omics data” and application thereof in prediction, prognosis and understanding of [...]
