NEWS
Prestigious ZonMw Open Competition grant awarded to LUMC, VU and RIVM
Prestigious ZonMw Open Competition grant awarded to LUMC, VU and RIVM Prestigious ZonMw Open Competition grant awarded to LUMC, VU and RIVM Our life expectancy keeps increasing on a global scale. The increase in healthy lifespan, however, is lagging behind. Members of long-lived families often remain disease-free into exceptionally old ages. How is this possible? A multi-disciplinary team of researchers from the LUMC, VU and RIVM received funding from ZonMw to answer this [...]
EU-project Rise-Well – cRitIcal Solutions for Elderly WELL-being
The goal of RISE-WELL is to improve SWB and QOL of elderly European citizens to obtain positive individual health outcomes and to promote future translational research. The approach of the consortium has been to design cutting-edge WPs and ESR projects. Scientific need: Mental health and emotional well-being during old age (60+) should be regarded as important as at any other time of a persons’ life. Older people are more likely to experience events that affect [...]
Leiden-Brazil Summer School on Data Science in Health and Disease – June 7 -17th 2021
This online summer course will stimulate international collaborations between students from Brazil and Leiden. The course will provide an introduction to the use of big data analysis in health and disease. The programme, including theory and practical modules, will focus on diverse hospital data, “omics data” and application thereof in prediction, prognosis and understanding of disease. Students will have the opportunity to interact with each other in culturally diverse groups. Brazil - Leiden cooperation on [...]
Signatures DuSRA – researchers on the website
In recent years, the DuSRA has developed into a serious discussion partner. Discussions have taken place with subsidy providers, such as ZonMW and Health-Holland. Meetings have been organized to learn about each other's expertise and collaborations have been started. A good example of this is VOILA. Now is the time to think about the future. We hear from our partners a need for cooperation, for example in the process of writing grants. In order [...]
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice
Aging Cell - February 2021 Dietary restriction (DR) and rapamycin extend healthspan and life span across multiple species. We have recently shown that DR in progeroid DNA repair-deficient mice dramatically extended healthspan and trippled life span. Here, we show that rapamycin, while significantly lowering mTOR signaling, failed to improve life span nor healthspan of DNA repair-deficient Ercc1∆/- mice, contrary to DR tested in parallel. Rapamycin interventions focusing on dosage, gender, and timing all were [...]
Welcome Trust Meeting on Longitudinal studies – March 9-12-2021
Due to the evolving situation with Covid-19, this meeting was postponed from 20-22 April 2020 and will now be held as a virtual conference. Longitudinal studies are ideal tools for studying many things including age-related functional changes, and the development and progression of chronic diseases. This conference will bring together scientists working on studies in childhood, adult and late life to identify novel biomarkers of functional decline and development of disease susceptibility, and to [...]
NWO Life2021 – call for abstracts staat open
Wat is NWO Life? Life is een uniek jaarlijks wetenschappelijk congres dat NWO organiseert voor alle levenswetenschappers binnen Nederland. In de volle breedte en op alle schaalniveaus: van femtometer tot kilometer, van cel tot planeet. NWO Life is bedoeld om senior en junior onderzoekers uit alle disciplines van het brede spectrum dat de Nederlandse levenswetenschappen omvat, te verbinden, te inspireren, grenzen te verkennen en te discussiëren over nieuwe en gewenste ontwikkelingen in het veld. [...]
Emerging Role of C/EBPβ and Epigenetic DNA Methylation in Ageing
Trends in genetics - Volume 36, Issue 2, February 2020 Christof Niehrs (Institute of Molecular Biology), Cornelis F. Calkhoven (European Research Institute for the Biology of Ageing) Ageing is closely associated with and influenced by energy metabolism, and C/EBPβ is emerging as a key regulator of energy metabolism and longevity. DNA hypermethylation in GADD45α/ING1 mutant mice is associated with progeria due to a failure of TET-dioxygenase mediated demethylation of C/EBPβ binding sites. Accordingly, GADD45α/ING1 mutant [...]
Vacature University of Michigan
Tenured and Tenure-Track Biogerontology Faculty Positions: University of Michigan The University of Michigan Geriatrics Center is seeking to hire one or more tenure track faculty members to carry out research focused on the biology of aging and the relationship of aging processes to late life diseases. We are interested in considering both new investigators, and also creative and successful mid-career or senior scientists whose research programs focus on questions related to aging. The ideal [...]
Happy New Year!
The DuSRA-board wishes all her members and their family a Healthy and Happy New Year!
