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Papers2018-01-22T10:49:36+01:00

Papers

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The Netherlands Consortium of Dementia Cohorts has performed a meta-analysis with 8 cohort studies to investigate the associations between depressive symptoms later in life and plasma markers for Alzheimer’s disease and neurodegeneration. The Leiden [...]

Aging Cell - February 2021 Dietary restriction (DR) and rapamycin extend healthspan and life span across multiple species. We have recently shown that DR in progeroid DNA repair-deficient mice dramatically extended healthspan and trippled [...]

Nature Communications - Augustus 2019 Human longevity is heritable, but genome-wide association (GWA) studies have had limited success. Here, we perform two meta-analyses of GWA studies of a rigorous longevity phenotype definition including 11,262/3484 [...]

Science Advances | 03-01-2018 Abstract Although it is assumed that epigenetic mechanisms, such as changes in DNA methylation (DNAm), underlie the relationship between adverse intrauterine conditions and adult metabolic health, evidence from human studies [...]

Experimental Gerontology | April 2017 | Abstract Populations of laboratory animals that are selected for increased lifespan often show negative correlated responses in early fecundity. However, late fecundity and/or total lifetime fecundity can be [...]

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